Enantioseparation by simulated moving bed chromatography: modeling, simulation ...

• Autor(es): Pais, L.S. ; Loureiro, José M. ; Rodrigues, A.E.
• Data: 1998
• Identificador Persistente: http://hdl.handle.net/10198/1491
• Origem: Biblioteca Digital do IPB
• Assunto(s): Simulated moving bed; Chiral separation
• Tipo de Documento: Documento de conferência
• Idioma: Inglês

Descrição

The paper deals with chiral separation by Simulated Moving Bed chromatography. A practical tool for choosing the better SMB operating conditions as a function of the feed flow rate is proposed. The operation of a pilot unit of SMB, Licosep 12-26 (Novasep, France), is carried out for the separation of bi-naphthol enantiomers. Experimental results and model predictions are compared in terms of process performance and internal concentration profiles.